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1.
Artigo em Inglês | MEDLINE | ID: mdl-38641005

RESUMO

INTRODUCTION: The average stroke morbidity rate, especially in rural communities, is higher when compared to the national average. OBJECTIVE: Identify the profile of knowledge and awareness of stroke in rural and urban communities and analyze the differences between the two. METHOD: Respondents who met the requirements answered a questionnaire containing a total of 41 items regarding knowledge and awareness of stroke. Characteristic data obtained includes age, gender, education, occupation, and ethnicity. Differences in characteristics were analyzed using Mann-Whitney, and the profiles of knowledge and awareness of stroke in rural and urban groups were analyzed using independent t tests to see differences between the two. RESULT: Differences in the characteristics of rural and urban groups were only in education (p = 0.036) and occupation (p = 0.021). The mean score of the knowledge domain for the rural group was 72.53 (SD = 11.04), for the urban group it was 81.06 (SD = 11.12). The mean score awareness of stroke domain in the rural group was 72.18 (SD = 11.01), the urban group was 85.51 (SD = 11.67). The profile of knowledge and awareness of stroke in rural communities was significantly lower than in urban communities. The significance value was (p = 0.004) for knowledge and (p = 0.002) for awareness of stroke. CONCLUSION: Based on the findings, it is reasonable to suspect that educational and occupational factors contribute to differences in the profile of knowledge and awareness of stroke in the two groups. Therefore, the stroke awareness campaign strategy for rural communities needs to be specifically designed by emphasizing/considering educational and occupational factors.

2.
J Public Health Res ; 12(3): 22799036231197172, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37667680

RESUMO

Background: The elderly with dementia occur cognitive decline and they are considered normal by the family, and then causing the need for care from elderly. This is not following the ability of home care by the family as an informal caregiver for the elderly with dementia. The purpose of this study was to analyze the effect of caregiver demands on the ability of families to do home care for elderly dementia. Design and methods: An analytical observational study with a cross-sectional design. The sample size is 100 respondents with a cluster random sampling technique. Data were collected by questionnaire and analyzed using SEM-PLS. Results: Caregiver demands have a direct effect on increasing the family's ability to do home care for elderly dementia with a p-value = 0.011 (p ≤ 0.05), t statistic value of 2.557 (≥1.96). Caregiver demands have four indicators, including care receiver impairment, caregiving activities, competency of caregivers, and caregiver/family relationship with elderly dementia. The condition of the elderly who experience various changes supports the increasing need for care to receive care and recovery as well as special attention from the family. Conclusion: The higher the need for care, the higher the family's ability to do home care. This research implies that the family has a duty in the health sector to provide care for the elderly at home/home care, which strengthens the need for care, this supports caregiver empowerment and increases the independence of the elderly with dementia.

3.
J Pak Med Assoc ; 73(Suppl 2)(2): S92-S95, 2023 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37096713

RESUMO

Objectives: To analyse patients' anxiety related to endoscopy. Method: The descriptive study was conducted from July 23 to September 14, 2020, at the Endoscopy Unit of Dr Abdoer Rahem Situbondo General Region Hospital, Dr Koesnadi Bondowoso General Region Hospital and Ibnu Sina Gresik General Region Hospital, East Java, Indonesia. The sample comprised endoscopy patients of either gender aged >20 years. Data was collected using the Endoscopy Confidence Questionnaire. RESULTS: Of the 50 patients, 28(56%) were males and 22(44%) were females. The largest age group was 41-50 years 17(34%), followed by 31-40 years 13(26%). Overall, 48(96%) subjects were married. Abdominal pain was most common indication for the procedure 10(20%). Esophagogastroduodenoscopy was the procedure in 29(58%) patients, 42(84%) had no history of endoscopy, and 41(82%) were reluctant to undergo the procedure. CONCLUSIONS: Patients' anxiety rises before endoscopy. Nurses need to provide complete and clear information related to the procedure, including the less pleasant elements.


Assuntos
Dor Abdominal , Endoscopia Gastrointestinal , Masculino , Feminino , Humanos , Ansiedade , Emoções , Inquéritos e Questionários
4.
F1000Res ; 12: 511, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38454922

RESUMO

Background: The COVID-19 pandemic has increased the need for mask production which has caused the problem of mask waste generating in the environment without being managed. This research was conducted to determine the relationship between knowledge, attitudes, and sociodemographic factors with college student behaviours in managing household mask waste in Daerah Khusus Ibukota (DKI) Jakarta Province. Methods: This study used a quantitative approach and cross-sectional study design. Data collection was carried out using an online questionnaire consisting of the respondents' sociodemographic, knowledge, attitudes, and behaviours. Results: The majority of students had high knowledge (63.3%), positive attitudes (52.5%), and good behaviours (50.6%). Statistically, there was a significant relationship between knowledge and behaviours (p = 0.022), but there was no significant relationship between attitudes and behaviours (p = 0.269). In addition, the sociodemographic factor variables showed a significant relationship between place of residence and behaviours (p = 0.008). However, there was no significant relationship between age, gender, education, and study program groups and behaviours (p > 0.05). Multivariate analysis showed that living with family was a dominant factor for bad behaviours (OR 1.664, 95% CI=1.124-2.464), and the second risk factor was the low level of knowledge has a significant relationship with the behaviours of mask waste management at home (OR=1.559, 95% CI=1.044-2.330). Conclusions: Students who live alone also show better behaviour compared to students who live with their families. The place of residence variable has the greatest influence on the behaviour of mask waste management at the household, followed by the knowledge variable.


Assuntos
COVID-19 , Humanos , COVID-19/epidemiologia , Conhecimentos, Atitudes e Prática em Saúde , Estudos Transversais , Pandemias , Máscaras , Estudantes
5.
J Public Health Res ; 11(4): 22799036221139939, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36466154

RESUMO

Introduction: There has been an increase in the usage of herbal remedies, particularly among pregnant women, across the globe. The prevalence of herbal medicine use during pregnancy ranged from 54.3% to 96.6% in the region studied, indicating a rising trend in the use of herbal medicine during pregnancy. Cold and flu symptoms and stomach problems were the most prevalent reasons people turned to this drug. Materials and methods: This study's samples were pregnant women in the working area of Ciwaruga Public Health Center, which has eight villages. The samples were taken using a proportional simple random sampling technique until 96 respondents were obtained. The percentage of moms who took herbal medication was the primary outcome variable, and participants were chosen for the research using a systematic sampling procedure. A digital database was used to store quantitative data that had been coded. Results: The factors significantly associated with the use of herbal medicines during pregnancy were perception (OR 2.18; CI 1.02-4.66), having ever used herbal medicines during a previous pregnancy (OR 3.87; CI 1.46-10.25), and healthy reproductive is other reasons (OR 7.98; CI 4.45-14.30). Conclusion: Pregnant women in the Ciwaruga Public Health Center area often turn to herbal remedies, which may indicate a lack of access to mainstream medical treatment. They believe that herbal medications are useful and that using them during a prior pregnancy is linked.

6.
RSC Adv ; 12(46): 29805-29812, 2022 Oct 17.
Artigo em Inglês | MEDLINE | ID: mdl-36321089

RESUMO

The plasma-enhanced chemical vapor deposition (PECVD) technique has been utilized for the facile surface deposition of hydrogenated diamond-like carbon (HDLC) thin-films onto Si(100) substrates. The as-deposited film surface is homogenous, free of pinholes, and adheres to the substrate. Annealing of the synthesized HDLC surface in a vacuum was performed in the temperature range of 200 to 1000 °C. A host of instrumental techniques, viz. FTIR spectroscopy, AFM, STM, and EC-AFM, were successfully employed to detect the morphological transformation in the HDLC films upon annealing. EC-AFM studies show irreversible biased behavior after undergoing a surface redox couple reaction and morphological change. Raman spectroscopy was carried out along with STM and EC-AFM to determine the functional nature and conductivity of the annealed surface.

7.
J Public Health Res ; 10(s2)2021 Dec 28.
Artigo em Inglês | MEDLINE | ID: mdl-34964570

RESUMO

BACKGROUND: Health and mortality problems are closely related to the maternal mortality rate (MMR). Efforts to reduce MMR have been carried out by many countries, including the Indonesian government. DESIGN AND METHODS: This research was conducted using two approaches, namely quantitative and qualitative or mixed methods and 149 respondents and 26 informants, to reduce MMR in Dairi Regency. This study was also carried out to determine the dominant variable that affects mother's behavior in an effort to reduce MMR in accordance with the existing theory. RESULT: Mother's intention to contribute to the reduction of MMR in this study was influenced by the good factor directly or indirectly. This is indicated by the score p<0.005. The study also shows that it is very important for the health workers to be able to communicate well with individuals and communities. CONCLUSION: The present study will help to reduce maternal fatalities, and will help to build systems and processes that will allow control the behaviour of the pregnant women and determine the cause of death as well as its contributing factors.

8.
J Public Health Res ; 10(s2)2021 Nov 24.
Artigo em Inglês | MEDLINE | ID: mdl-34818881

RESUMO

BACKGROUND: Dadiah is a traditional dish from West Sumatra made from buffalo milk, which is fermented in bamboo tubes and left at room temperature for ±2 days. Dadiah is included in the staple food category because it contains Lactic Acid Bacteria (LAB), which has the potential to be a probiotic. This study aims to determine the identification and characterization of LAB from Dadiah from Halaban, Kab. Fifty Cities, West Sumatra. DESIGN AND METHODS: A survey method was used in this research with a descriptive analysis, Antimicrobial activity testing was done with bacteria Escherichia coli O157, Staphylococcus aureus, Listeria monocytogenes, and Listeria innocua. Molecular identification was done using the 16S rRNA gene. RESULTS: Probiotic candidate test with the best results in testing for resistance to stomach acid at pH3 with the viability of 65.98%, bile salt resistance 0.3%, viability of 54.90% from 2DA isolates. Antimicrobial activity with the best clear zone area results was obtained in 2DA isolates with Escherichia coli O157 test bacteria of 21.16 mm, Staphylococcus aureus with a clear zone area of 23.17 mm, Listeria innocua of 19.24 mm and Listeria monocytogenes with a clear zone area 18.23 mm in 4DA isolate, LAB identification using 16S sRNA gene, results of running PCR base length 1419bp. CONCLUSIONS: Phylogenetic analysis shows that Dadiah of Limapuluh Kota Regency is a kin to Lactobacillus plantarum. The superiority of identification technology by using 16S rRNA gene only can be conducted if the nucleotide sequence information of the targeted bacteria is known beforehand.

9.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 1-5, jun. 2020. graf, tab
Artigo em Inglês | IBECS | ID: ibc-196464

RESUMO

BACKGROUND: Communication in adolesencest is an interpersonal interaction that use symbolic linguistic system, such as a system of verbal and non-verbal symbols. Factors that influence adolescent communication include environmental factors, education, and online games. Research objectives: To find out the correlation between frequency of playing online games and teen communication on students' Level I & II of STIKes Muhammadiyah Palembang. Research method: the research method use was quantitative descriptive research with Cross Sectional approach using Purposive Sampling as the technique of collecting data with a simple of 262 out of 760 populations. The instrument used in the form of a questionnaire about the frequency of playing online games and teen communication made by the researcher and has been tested for validity and reliability. This research was conducted in March-April 2019. RESULT: From the results of the study, most of the respondents with 116 respondents (82.3%) had passive communication with the frequency of playing online games often, and a small number of respondents with 2 respondents (2.9%) had aggressive communication with the frequency of playing online games sometimes. The result test of Chi Square was obtained a value P value=0.000 (<0.05). CONCLUSION:There was a correlation between frequency of playing online games and teen communication on students' level I & II STIKes Muhammadiyah Palembang


No disponible


Assuntos
Humanos , Comportamento do Adolescente/psicologia , Comportamento Aditivo/psicologia , Estudantes de Enfermagem/estatística & dados numéricos , Comunicação , Jogos de Vídeo/psicologia , Relações Interpessoais , Estudos Transversais , Inquéritos e Questionários , Internet
10.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 92-95, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196483

RESUMO

The toddler stage is a golden period and at the same time a critical period for a child, since he / she will experience rapid brain growth and development so that he/ she need sufficient nutrition intake. Toddler's abnormal growth and development are usually found in low economic community because they cannot afford to provide their need for basic food for their toddler's growth and development. The objective of the research was to analyze toddler's growth and development according to family's economic status. The research used descriptive analytic method with cross-sectional design. It was conducted at Limau Manis Village, Tanjung Morawa Subdistrict, Deli Serdang Regency, from January to June 2016. The population was 1899 toddlers, and 113 of them were used as the samples, taken by using simple random sampling technique. The data were gathered by using questionnaires to find out toddler's growth and development according to family's economic status. The result of univariate analysis showed that 57 toddlers (50.4%) had abnormal growth and development. The result of bivariate analysis with chi-square test showed that there was the correlation of toddler's growth and development with economic status (p value=0.004), women's care pattern (p value=0.028), and environmental sanitation (p value=0.01). Therefore, empowerment of family's economy through the development of family's nutrition portfolio is necessary


No disponible


Assuntos
Humanos , Desenvolvimento Infantil , Status Econômico , Família , Estado Nutricional , Indonésia , Estudos Transversais , Meio Ambiente , Cuidado da Criança
11.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 115-118, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196489

RESUMO

The purpose of this study is to determine whether there are differences in hemoglobin levels before and after consuming ambon bananas in students of Prodi Kebidanan Metro. The specific purpose of this study was to determine hemoglobin levels before consuming ambon bananas, hemoglobin levels after consuming ambon bananas and the differences in hemoglobin levels before and after consuming ambon bananas in female students at Prodi Kebidanan Metro. This research is an intervention research with quasi experiment design with The One Group Pretest - posttest design. The population in this study were students in the first and second grade in Prodi Kebidanan Metro who lived in the dormitory as many as 149 female students. A sample of 49 people will take a portion of the population using simple random sampling technique. Data analysis used dependent sample t tests to test the mean increase in Hb levels before and after consuming ambon bananas. The results showed an average Hb level before consuming bananas at 12.51g/dl and an the average hb level after consuming bananas was 12.89g/dl, so the average increase in Hb levels was 0.39g/dl. The results of the analysis using the t-test dependent test obtained p value=0.000, which means that there are significant differences in Hb levels of students before and after consuming ambon banana


No disponible


Assuntos
Humanos , Feminino , Adolescente , Adulto Jovem , Adulto , Pessoa de Meia-Idade , Hemoglobinas/metabolismo , Índices de Eritrócitos/fisiologia , Musa/classificação , Estudantes/estatística & dados numéricos , Extratos Vegetais/administração & dosagem , Frutas/química , Frutas/metabolismo , Estado Nutricional , Hemoglobinas/análise
12.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 129-132, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196492

RESUMO

Postpartum depression (PPD) is quite large, where there are 1 in 25 postpartum women experiencing PPD who still report symptoms of PPD after six months. The highest risk of experiencing PPD is more experienced by primiparas detected in 10-19 postpartum days. For PPD to not adversely affect the mother and baby, initial screening is needed to prevent the occurrence of PPD by using an Android-based EPDS application. The research objectives are an early screening of baby blues based on Android application and to determine the factors influence of baby blues. Participants download EPDS apps to make it easier for participants to screen the baby blues at the beginning of the first week after giving birth. On fourth week, the mothers refill EPDS apps screening to compare the results of screening the first week with fourth week using the Dependent T-test. In this study also analyzed the factors that influence the baby blues such as education, employment, parity, and age using the ANOVA Test. The study sample was the first-week postpartum mothers with a total sample of 64 people. The average EPDS screening results in the first week were 6.64, with a standard deviation of 2.57. The screening results on fourth week are 6.70, with a standard deviation of 2.53. The results of statistical tests obtained p-value 0.208; it can conclude that there was no difference in the results of screening tests in the first week with the fourth week. PPD events occur mostly in primiparas and women aged <20 years with p-value 0.001, while in education p-value 0.596 and employment-value 0.784. It recommended for pregnant women and health workers to do screening in the first week of postpartum so that it can detect PPD early


No disponible


Assuntos
Humanos , Feminino , Adulto Jovem , Adulto , Diagnóstico Precoce , Transtornos Puerperais/diagnóstico , Aplicativos Móveis , Depressão Pós-Parto/diagnóstico , Análise de Variância , Período Pós-Parto
13.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 171-174, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196662

RESUMO

OBJECTIVE: Pain management is one of the methods used in the health sector. Nursing care focuses on non-pharmacological measures, including the provision of aromatherapy using lavender and rose aromatherapy, which aims to understand the effectiveness of lavender and rose aromatherapy on pain intensity of postoperative patients in Laparatomi Hospital in Aisyiyah General Hospital in the surgical inpatient room, Padang in 2019. METHOD: The design of this study is a Quasi Experiment with pre-test and post-test designs with two groups. The sample of this study was Post Laparatomi in RSU with the technique of Accidental Sampling. The sample of this study consisted of 30 people for lavender and rose aromatherapy. Statistical tests used the Independent Test T-test. RESULT: Based on the results of the study it was found that lavender and rose aromatherapy can reduce pain scale in postoperative patients. But compared to the two intervention groups, the aroma group of lavender therapy is more effective with mean pain scale before lavender aromatherapy being 5.20 and pre-test is 3.40 with p-value 0.000. CONCLUSION: The nurses could provide nursing care in dealing with pain management in postoperative patients in addition to deep breathing techniques. It is recommended to apply aroma lavender therapy, which reduces pain and makes patients more relaxed


No disponible


Assuntos
Humanos , Aromaterapia/enfermagem , Óleos de Plantas/uso terapêutico , Dor Pós-Operatória/enfermagem , Dor Pós-Operatória/terapia , Papel do Profissional de Enfermagem , Aromaterapia/métodos , Rosa , Lavandula , Dor Pós-Operatória , Cuidados Pós-Operatórios/enfermagem
14.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 188-191, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196666

RESUMO

OBJECTIVE: The purpose of this study was to identify the nurse's overall experience with a mentoring programme and the study specifically seeks to determine the attitudes and perceived benefits of students in different semesters regarding the mentoring programme. METHOD: The research design was quantitative. Face-to-face survey method based on a given questionnaire was conducted with all the targeted respondents. The methodology used was a non-experimental descriptive research design. Total of 146 respondents out of 243 populations were selected using a stratified random sampling strategy to determine the research sample to give equal opportunity. RESULTS: Findings of hypotheses test using one-way ANOVA indicated that there is a significant difference in attitudes towards the mentoring programme and perceived benefits between different groups of nursing at Training Institute Ministry of Health (Nursing) Sandakan. CONCLUSION: In general, the mentoring programme had a positive impact. However, the level of attitude and perceived benefit is different among students in different semesters. The overall mean result is good and reflecting nursing students are fairly benefited from the mentoring programme


No disponible


Assuntos
Humanos , Estudantes de Enfermagem/estatística & dados numéricos , Mentores , Pesquisa em Enfermagem/organização & administração , Bacharelado em Enfermagem , Estudantes de Enfermagem/psicologia , Análise de Variância
15.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 202-205, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196669

RESUMO

Based on preliminary studies, it is known that 80% of working mothers fail to make exclusive breastfeeding, on average babies are given formula milk 2-4 months old and stop breastfeeding at 6-18 months of age. Papaya leaves are one of the galactagogues that contain quercetin which can activate the hormone prolactin and help increase breastmilk. The purpose of this study was to determine the effect of giving papaya leaf juice for nursing mothers who work toward increasing levels of the hormone prolactin and infant weight in Tangerang. The research design used was a pre-experimental model with one group pretest-posttest design. Samples taken as many as 10 mothers who have babies aged 0-6 months who have difficulty in breastfeeding because the amount of breastmilk was a little. The study was conducted in several clinics in Tangerang. The intervention was giving papaya leaf juice for 7 consecutive days. The results obtained from this study are as follows: 90% of mothers aged between 20 and 35 years, 70% of mothers have a history of spontaneous labor and have no complications at the time of delivery, 40% of mother's education is junior high school (SMP), and 70% of mothers are primiparas. The average increase in the amount of prolactin after the intervention was 19.59ng/ml, while the average weight gain of the newborn after the intervention was 165g. Wilcoxon test results for increased levels of the hormone prolactin p-value of 0.047<0.05 and for an increase in body weight of newborns p-value of 0.009<0.05. CONCLUSION: There is an effect of giving papaya leaf juice for nursing mothers who work on increasing levels of the hormone prolactin and infant weight in Tangerang. Papaya leaf juice can be a galactagogue for mothers who experience problems with a small amount of breastmilk


No disponible


Assuntos
Humanos , Masculino , Feminino , Recém-Nascido , Lactente , Adulto , Carica/metabolismo , Aleitamento Materno/métodos , Hormônio Liberador de Prolactina , Leite Humano/metabolismo , Mães , Comportamento Alimentar , Glândulas Mamárias Humanas/metabolismo , Glândulas Mamárias Humanas/fisiologia , Prolactina/metabolismo
16.
Enferm. clín. (Ed. impr.) ; 30(supl.5): 228-233, jun. 2020. tab
Artigo em Inglês | IBECS | ID: ibc-196676

RESUMO

INTRODUCTION: Cases of trauma still becomes a health problem in almost all countries causing death in few cases. In some developing countries, the insidences of head injury tend to increase. One of the reasons for the many death and disability may be due to the inavailability and inadequacy of pre-hospital first aid. AIM: The general objective of this study is to find out the description of community first responder in providing pre-hospital first aid to head injuries. METHODS: This study uses qualitative descriptive method. RESULTS: Most of the respondents have variety of educational backgrounds and do not have sufficient knowledge and skills to provide first aid. The average respondents provided help by performing initial assessment, managing effective airway and controlling bleeding. Limited pre-hospital facilities become one of the reasons for respondent not getting help so the efforts provided are not maximal. Respondents prefer to send patients directly to health facilities. CONCLUSION: Regular education and training programs for the community first responders should be initiated so that the number of death and disability can be minimized


No disponible


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Serviço Hospitalar de Emergência , Serviços Médicos de Emergência , Traumatismos Craniocerebrais/epidemiologia , Serviços Pré-Hospitalares , Lesões Encefálicas Traumáticas/epidemiologia , Traumatismos Craniocerebrais/diagnóstico , Traumatismos Craniocerebrais/terapia , 25783 , Inquéritos e Questionários , Acidentes de Trânsito/estatística & dados numéricos
17.
Oncol Res ; 17(9): 397-403, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19718946

RESUMO

Individual cancer susceptibility is the result of several host factors, including differences in lifestyle habits and genetic susceptibility. There is a correlation between CYP1A1 polymorphism (MspI) and oral cancer susceptibility. Individuals carrying the deletions of GSTM1 and GSTT1 are at high risk of developing oral cancers. In the present study on healthy tribal and nontribal individuals of Assam, we found that the genetic variation of GSST polymorphisms is evident (p = 0.20) with differential dose of toxic exposure. Prevalence of different polymorphic alleles of CYP1A1 also proves the same result. A mini-case-control study with very small sample size showed no marked increase in the risk of developing oral cancer as the frequencies of the studied GST genotypes did not show any statistical significance. But GSTT1-null genotypes were found to have higher risk of developing leukoplakia (OR 1.94, 95% CI 2.61-18.54). CYP1A1 genotype m2 allele was also not found to be associated with the risk of developing leukoplakias in the population.


Assuntos
Citocromo P-450 CYP1A1/genética , Predisposição Genética para Doença , Glutationa Transferase/genética , Neoplasias Bucais/genética , Polimorfismo Genético , Adolescente , Adulto , Idoso , Criança , Feminino , Genótipo , Humanos , Índia , Leucoplasia/etiologia , Leucoplasia/genética , Masculino , Pessoa de Meia-Idade , Neoplasias Bucais/etiologia , Fumar/efeitos adversos
18.
Hemoglobin ; 29(4): 277-80, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16370488

RESUMO

Five hundred and thirteen unrelated subjects belonging to various tribes of West Bengal, Arunachal Pradesh and Assam in Eastern India, were screened for the presence of alpha-thalassemia (thal) gene deletion(s) as a possible cause of unexplained anemia (Hb < 11 g/dL and/or MCH <28 pg, MCV < 78 fL). As reported earlier, beta-globin gene mutant alleles were found with a frequency of up to 20% in some tribes. In the present study, alpha-globin gene deletion alleles were found in 18% of subjects from West Bengal, 3.9% from Arunachal Pradesh and 3.84% from Assam tribesmen. Coexistence of alpha- and beta-globin gene abnormalities was observed in up to 18% of some tribal groups. The high inbreeding rate and lack of appropriate medical care make these populations particularly vulnerable.


Assuntos
Epidemiologia Molecular , Talassemia alfa/epidemiologia , Consanguinidade , Frequência do Gene , Testes Genéticos , Globinas/genética , Humanos , Índia/epidemiologia , Índia/etnologia , Grupos Populacionais/genética , Talassemia alfa/diagnóstico , Talassemia alfa/genética
19.
Indian J Exp Biol ; 42(9): 900-3, 2004 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-15462183

RESUMO

The relative efficacy of infusion of black tea leaf, Camellia sinensis (Linn.) O. Kuntze, (Theaceae), and iron as freshly prepared aqueous solution of ferrous sulphate in reducing the cytotoxic effects of arsenic, was tested in bone marrow cells of laboratory bred Swiss albino mice. Ferrous sulphate and tea given alone did not induce chromosomal breakage to any appreciable extent. Tea decreased chromosome damage induced by arsenic to a significant extent, while the addition of ferrous sulphate did not alter the protective action of tea against arsenic. Such protection against arsenic cytotoxicity by prolonged dietary administration of black tea infusion--a common routine beverage--is of importance in view of widespread exposure of human populations to arsenic damage through drinking water from tubewells in Eastern India and Bangladesh.


Assuntos
Intoxicação por Arsênico/dietoterapia , Arsênio/toxicidade , Células da Medula Óssea/efeitos dos fármacos , Quebra Cromossômica , Dieta , Compostos Ferrosos/uso terapêutico , Chá , Animais , Intoxicação por Arsênico/prevenção & controle , Divisão Celular/efeitos dos fármacos , Feminino , Masculino , Camundongos , Espécies Reativas de Oxigênio
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